The action begins on BT Sport 1 HD and BT Sport 4K UHD from 8pm as Warrington aims to avoid a potential banana skin on his quest to become a unified world featherweight champion by taking care of the mandatory challenger to his IBF strap, Kid Galahad.
Domestic super-welterweight rivals JJ Metcalf and Jason Welborn go toe-to-toe in another eye-catching bout at Leeds' First Direct Arena having promised to steal the show with a "bloodbath" for the vacant commonwealth championship.
And another all-British clash certain to keep fans entertained sees explosive super-featherweights Zelfa Barrett and Lyon Woodstock trade leather for commonwealth honours, while a host of other promising young fighters will also be in action on another bumper night of boxing.
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Warrington v Galahad: Fight preview
The bright lights and big arenas in Las Vegas appeared to be beckoning for Josh Warrington after he clobbered Carl Frampton over 12 rounds during a thrilling victory back in December.
However, the International Boxing Federation had other ideas, pouring cold water on his dreams of going stateside in search of a unification clash by calling him to face mandatory challenger Kid Galahad.
But June 15 will not be the first time the pair have shared the ring together.
As Yorkshire rivals, they boxed in the amateur ranks and it was the "Leeds Warrior" who triumphed twice over Sheffield prospect Galahad.
“I will go into this fight as the bookies’ favourite, but I will be 100 per-cent focused and looking to do a job," Warrington, 28-0, said.
"I knew Barry [Awad, Galahad’s real name] when we were amateurs and he was always a decent guy, but over the last few years he seems to have changed and put on some persona to blag fans, opponents or himself.
"He did well at super-bantamweight, but he has beaten nobody as a featherweight and he has lost respect from me for some of his antics.
"I want to be Ring Magazine champion, own all the belts and they are in touching distance. I can beat all the featherweights.
"I am concentrating purely on Barry, but after this I want one of the other world champions. I want champion after champion."
With Anthony Joshua’s shock defeat to Andy Ruiz Jr still fresh in the memory, both men will have been delivered a timely reminder of boxing’s unforgiving nature as more lucrative clashes lurk tantalisingly on the horizon.
And Galahad believes he could capitalise on Warrington’s lack of focus when the pair go to war on Saturday night.
"To a certain extent, with him having hit the highs, having to come back and fight 'Barry from Sheffield' is a bit of a downer for him," the 26-0 challenger explained.
"He and his team thought they were off to Vegas and fighting Oscar Valdez and all these other guys. On June 15 I don't believe he thinks it is going to be an easy fight, he knows it will be a hard one.
"At this moment Josh might be confident because he beat [Lee] Selby and [Carl] Frampton who he thinks are better than me, but when he gets in the ring he’ll wish he never took this fight.
"The timing for when he beat Selby and Frampton was perfect. Selby was struggling to make the weight and Carl hasn’t been the same for three or four years.
"I think Josh’s win over Selby was so much better than the Frampton win. I just believe he is fighting a strong featherweight who is in his prime and I believe in his head he knows what is going to happen."
Warrington v Galahad: Who else is fighting?
British boxing takes centre stage on the Warrington v Galahad undercard this weekend with two domestic 12-round title affairs as well as a host of promising young talent in action.
The evening’s chief support could turn out to be the fight of the night as fan-friendly duo JJ Metcalf and Jason Welborn face off for the Commonwealth super welterweight strap.
“It will be a bloodbath,” Welborn promised.
“We will go looking for each other. I don’t think we know any other way of fighting and I can’t wait.”
“It is a tough fight,” Metcalf added, “but one that I can win.
“Jason has had a very good career, is very tough, busy and I cannot take nothing away from what he has achieved.
“I’ve not reached my peak yet, but these are the sort of tests I need at this stage of my career.
“I have been a prospect for too long, but now is the time to start winning big titles and getting to world level.”
Elsewhere, promising youngsters Zelfa Barrett and Lyon Woodstock will also have the chance to claim Commonwealth gold as they tango for the super-featherweight strap.
At 25, both men are looking to take the next step in their careers that would move them towards the European stage but Barrett has full confidence he will be the man to have his arm raised at the First Direct Arena.
“I believe in myself, I believe in my style and I believe in everything I do, so I believe 100 per cent that I have the beating of Woodstock, while he will believe in himself and his style, which is why he has taken the fight,” the 21-1 fighter said.
“My style will beat his, but I do rate him and he is a good fighter who does things well. He is an aggressive fighter coming forward, he can box a bit, has got a bit of power and is a respectable opponent.
“I need this kind of fight to bring the best out in me.”
But ice-cool Woodstock, 12-1, shrugged off the pressure, claiming it will just be another day in the office for him.
“I will just go in there and do what I do,” the Leicester man said.
"Every fight excites me, whether I am in with a journeyman or a good opponent, I just love fighting and I know I will finish where I am supposed to finish.
"This is just a stepping stone towards there, which will be a world title. There will be no loser really and it is better to have these fights now because it will hold you in good stead for later on at world level.
"It will not be the end of anyone and it would ruin anybody’s career.
"I just know I will do what I’ve gotta do to pick up the W. I know what I am going in there to do and it is going to be a good fight on the night, that’s what I know. I am not apprehensive or anything, it is just a fight.”
Light heavyweight prospect Lyndon Arthur will also be in action on Saturday night, taking on Andrzej Soldra over eight rounds, while Troy Williamson, Alex Dickinson, Mark Heffron, Jack McGann, Jack Bareson and Shakiel Thompson round off the rest of the card.
Warrington v Galahad: Selected odds
Josh Warrington 1/3 v Kid Galahad 12/5
James Metcalf 4/9 v Jason Welborn 13/8
Zelfa Barrett 2/7 v Leon Woodstock 5/2
Troy Williamson 1/20 v Edwin Palacios 8/1
Lyndon Arthur 1/33 v Andrzej Soldra 9/1
All odds correct with Bet365 at the time of writing