Coverage of the clash begins at 7pm with the match available on BT Sport 2 and BT Sport 4K UHD - kick off is at 7:45pm.
The game is part of a massive weekend of European rugby in the penultimate round of pool-stage games.
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Gloucester v Munster: Match preview
Gloucester welcome Munster to Kingsholm on Friday night knowing nothing less than victory will keep their slim hopes alive of reaching the quarter-finals of the competition.
Johann Ackermann's Cherry and Whites will be desperate to bounce back after suffering successive defeats in the Gallagher Premiership but face a stern test against Pool Two leaders Munster.
Gloucester sit bottom of the pool following a home defeat to Exeter Chiefs last time out in Europe but they - along with the other three teams - still stand a mathematical chance of progressing and Ackermann is in optimistic mood ahead of Friday's showdown under the lights.
“It’s going to be challenging for us now to be involved, but we’ll take it when we get to that next hurdle with Munster at home and see where we are, and reassess what we need to do,” he said.
The first meeting between the two sides - a 36-22 victory for Munster in October - was marred by a controversial red card for Gloucester Danny Cipriani.
Speaking earlier this week, Ackermann admitted the decision still rankles with him.
"It was frustrating for me, the fact that we will never know the influence of the card. I'm not saying we were going to win, but we finished the game strongly and did so many good things up until the red card.
"After the card we had a block where we struggled to adapt, but once we did that we finished well.
"A few weeks later, it was quite clear the tackle could have only been a yellow card. By then it's too late, but it was frustrating because you are up against a quality team and a red card makes life even harder."
A win for Munster is paramount if the Irish province are to have any hope of guaranteeing a home quarter-final after failing to beat Castres in round five.
Munster captain Peter O'Mahony says he is expecting a raucous atmosphere at Kingsholm come Friday evening.
“I have been going there since I was small supporting Munster. It’s an incredible atmosphere,” he said.
“They have an incredible passion for their team and their support around Europe is second to none.
“I just remember the noise, looking across at the Shed and the racket they make. I suppose they are similar to our own group [of fans] with how passionate and loyal they are.
“It’s always a great place, whether you’re a fan or whether you’re on the pitch. The atmosphere over there is certainly something you notice.”
With all four teams in Pool Two separated by just four points, it's a game neither side can afford to lose.
Gloucester v Munster: Team news
15. Tom Hudson, 14. Charlie Sharples, 13. Billy Twelvetrees, 12. Mark Atkinson, 11. Ollie Thorley, 10. Danny Cipriani, 9. Callum Braley; 1. Josh Hohneck, 2. Henry Walker, 3. Fraser Balmain; 4. Ed Slater, 5. Gerbrandt Grobler; 6. Franco Mostert, 7. Lewis Ludlow, 8. Ben Morgan (capt)
16. Franco Marais, 17. Alex Seville, 18. Ciaran Knight; 19. Freddie Clarke, 20. Gareth Evans; 21. Ben Vellacott, 22. Owen Williams, 23. Henry Trinder
15. Mike Haley, 14. Andrew Conway, 13. Chris Farrell, 12. Rory Scannell, 11. Keith Earls; 10. Joey Carbery, 9. Conor Murray; 1. Dave Kilcoyne, 2. Niall Scannell, 3. Stephen Archer; 4. Jean Kleyn, 5. Tadgh Beirne; 6. Peter O’Mahony (capt), 7. Tommy O’Donnell, 8. CJ Stander
16. Rhys Marshall, 17. Jeremy Loughman, 18. John Ryan; 19. Billy Holland, 20. Arno Botha, 21. Alby Mathewson, 22. Tyler Bleyendaal, 23. Dan Goggin
Danny Cipriani is set to return at fly-half, despite fears the 30-year-old would miss the game.
Cipriani has been named at fly-half after recovering from a chest injury sustained in December's pool game against Exeter.
Ollie Thornley, who won the Gallagher Premiership player of the month award for December, returns on the left wing while Henry Walker comes in at hooker.
For Munster, Ireland's Chris Farrell is a surprise inclusion after recovering from a right knee injury following a late fitness assessment by the club's medical department.
John Ryan was removed as a precaution for a head injury assessment in the first half of Saturday night’s game. He has completed the HIA process and has been cleared to train.
Chris Cloete (neck) will be reintegrated into team training this week while JJ Hanrahan is a doubt and will be assessed by the medical department for a left hip injury.
Gloucester v Munster: The Coaches
Munster head coach Johann van Graan: “There’s no lack of motivation or excitement for this week. I think the key from the coaching point of view is to actually hold them back and not to waste unnecessary energy before we take the field on Friday night.
“I’ve never been to that stadium [Kingsholm] before but what I’ve read and what I’ve heard, it’s an incredible place, it’s a sell-out and it’s Munster versus Gloucester. There’s so much history between the clubs so it will be a fantastic rugby occasion on Friday night.
“That’s why I came to the Northern Hemisphere, for days like Friday evening. You’ve got the best players in both leagues that are going to go for each other and the winner over the next two weeks between the four teams, there’s a quarter-final spot available so we have to look forward to it.”
Gloucester head coach Ackermann: "We've learned lessons from the past two weeks and implemented them into our training to try and get better.
"But we've not been sulking about it. Friday's challenge is massive and, if you go into it with a negative mindset, it's not going to help."
Gloucester v Munster: Head-to-head:
|20/10/2018||Champions Cup||Munster 36-22 Gloucester|
|11/01/2014||Champions Cup||Gloucester 7-20 Munster|
|19/10/2013||Champions Cup||Munster 26-10 Gloucester|
|05/04/2008||Champions Cup||Gloucester 3-16 Munster|
|17/01/2004||Champions Cup||Munster 35-14 Gloucester|
Gloucester v Munster: Match facts
Munster have won each of their last five meetings with Gloucester Rugby, those victories all coming by more than 12 points.
Munster’s last six away games have all been decided by single figure margins, with their record evenly split in that period, winning twice, drawing twice and losing twice.
Gloucester Rugby have won six of their eight European Cup games when hosting Irish opposition (L2), however, their two defeats have both come against Munster.
Munster have stolen 10 lineouts this season, more than any other side after four rounds of action.
- Munster’s Peter O’Mahony has stolen five lineouts this season, more than any other player and one more than Gloucester’s Gerbrandt Grobler who has stolen the second most (4, level with Ben Toolis of Edinburgh). O’Mahony has conceded the most penalties to date (9)
Gloucester v Munster: Betting odds
Gloucester +5: 10/11
Draw +5: 25/1
Munster -5: 10/11