Manchester City put their unbeaten record on the line when they take on Chelsea at Stamford Bridge on Saturday (live on BT Sport 1, 5.30pm kick-off).
Pep Guardiola’s side have won four in a row in the league, scoring 18 goals and conceding just one in the process, while champions Chelsea have reeled off a five-game unbeaten run, picking up 13 points, since their shock opening-day reverse to Burnley.
Tottenham head to Huddersfield in the early game on Saturday while rock-bottom Crystal Palace face another tough assignment as they meet Manchester United at Old Trafford.
Arsenal host Brighton on Sunday with Liverpool also in action when they face Newcastle at St James’ Park.
Saturday September 30
AFC Bournemouth (19) v Leicester (17)
Bournemouth team news: Bournemouth look set to be without midfielder Harry Arter again because of an Achilles problem. Dan Gosling (knock) is also a doubt along with defender Tyrone Mings (back), while forward Callum Wilson has resumed some training following his long-term knee injury.
Eddie Howe: “I am not sure it ever gets easier in the Premier League. As everyone knows it is an incredibly difficult and demanding league in many different ways.”
Leicester team news: Jamie Vardy (hip) will be assessed having only trained for the first time this week on Thursday. Robert Huth, who underwent ankle surgery in the summer, and Matty James (Achilles) remain out.
Craig Shakespeare: “It will be a big challenge. It has not been the best start for Bournemouth but both teams will aim for three points.”
Last season: Leicester 1 AFC Bournemouth 1, AFC Bournemouth 1 Leicester 0
Last five league matches: AFC Bournemouth L L L W L; Leicester W L L D L
Top scorers: Joshua King (AFC Bournemouth) 2; Jamie Vardy (Leicester) 5
Match odds: H 7-4 A 6-4 D 12-5
Referee: Graham Scott (Oxfordshire)
Chelsea (3) v Man City (1)
Chelsea team news: Eden Hazard is expected to start in the Premier League for the first time this season. Defender David Luiz completes his three-match domestic ban with Andreas Christensen poised to deputise. Midfielder Danny Drinkwater (calf) is out.
Antonio Conte: “If he (Hazard) was able to play one game like the last game against Atletico Madrid it means he’s ready now to play with continuity.”
Man City team news: Leaders Manchester City will be without Sergio Aguero after the striker suffered rib injuries in a car crash on Thursday. Left-back Benjamin Mendy (anterior cruciate ligament) and captain Vincent Kompany (calf) are sidelined.
Pep Guardiola: “I think the players have to rest mentally and physically. They can enjoy their lives. I want my players to have fun. If they decide to go there, they decide to go there. It is okay for me.”
Last season: Chelsea 2 Man City 1, Man City 1 Chelsea 3
Last five league matches: Chelsea W W W D W; Man City D W W W W
Top scorers: Alvaro Morata (Chelsea) 6; Sergio Aguero (Man City) 7
Match odds: H 9-5 A 6-4 D 23-10
Referee: Martin Atkinson (W Yorkshire)
Huddersfield (8) v Tottenham (4)
Huddersfield team news: Club-record signing Steve Mounie is still struggling with a foot injury. Collin Quaner (knee), Kasey Palmer (hamstring) and Danny Williams (foot) remain sidelined.
David Wagner: “This is the first time we meet an opponent of this quality, it’s the next step. But this group so far has taken every step as well as they could and now we are looking to see if we can take the next one.”
Tottenham team news: Christian Eriksen should return after missing the Champions League game against Apoel Nicosia in midweek through illness. Jan Vertonghen and Dele Alli return after European suspensions but Serge Aurier is banned.
Mauricio Pochettino (on Dele Alli): “He’s more mature today. I think you can feel the same that he’s more mature, he’s not the kid who arrived here three years ago. A lot of things happened in that period.”
Last season: No Corresponding fixture
Last five league matches: Huddersfield W D L D D; Tottenham L D W D W
Top scorers: Steve Mounie (Huddersfield) 2; Harry Kane (Tottenham) 9
Match odds: H 7-1 A 2-5 D 7-2
Referee: Neil Swarbrick (Lancashire)
Man Utd (2) v Crystal Palace (20)
Man Utd team news: Michael Carrick joins Paul Pogba, Marcos Rojo and Zlatan Ibrahimovic on the sidelines, while Phil Jones and Antonio Valencia will be assessed. Maroaune Fellaini (ankle) is still under assessment, while Anthony Martial went off in the 4-1 win in Russia.
Jose Mourinho (on Paul Pogba): “He’s injured, he cannot play tomorrow and it’s not an injury that I can have the hope like I have with (Antonio) Valencia or (Phil) Jones.”
Palace team news: Rookie forward Freddie Ladapo is Palace’s only fit recognised striker after Christian Benteke (knee) was ruled out for at least six weeks. Bakary Sako could be a makeshift striker. Ruben Loftus-Cheek (thigh) and James Tomkins (illess) are sidelined.
Roy Hodgson: “Freddie Ladapo has been training with the first team for quite a while now. He’s an unknown quantity, for me certainly.”
Last season: Man Utd 2 Crystal Palace 0, Crystal Palace 1 Man Utd 2
Last five league matches: Man Utd W W D W W; Crystal Palace L L L L L
Top scorers: Romelu Lukaku (Man Utd) 8; James McArthur (Crystal Palace) 2
Match odds: H 1-6 A 16-1 D 6-1
Referee: Mike Dean (Wirral)
Stoke (16) v Southampton (11)
Stoke team news: Bruno Martins Indi (groin) is Stoke’s latest absentee, while Ryan Shawcross (back) is also missing and both Geoff Cameron and Kevin Wimmer (both hamstring) are rated doubtful. Kurt Zouma returns and full-backs Glen Johnson and Erik Pieters are also options.
Mark Hughes: “Clearly Jack (Butland) knows he has to have an outstanding season for us to make sure he travels with them (England) and he pushes the guy in charge and wearing the shirt at the moment.”
Southampton team news: Virgil van Dijk could remain on the bench for the trip to Stoke. Saints boss Mauricio Pellegrino insists the Holland defender must remain patient on his reintegration. Matt Targett (ankle) is a doubt.
Mauricio Pellegrino: “Being better in the final third, it’s not about more strikers, wingers or pushing the full-backs higher – it’s just about quality in the final third.”
Last season: Southampton 0 Stoke 1, Stoke 0 Southampton 0
Last five league matches: Stoke W D D L L; Southampton W D L W L
Top scorers: Eric Maxim Choupo-Moting, Peter Crouch & Joe Allen (Stoke) 2; Steven Davis, Charlie Austin, Manolo Gabbiadini & Dusan Tadic (Southampton) 1,
Match odds: H 19-10 A 6-4 D 11-5
Referee: Mike Jones (Cheshire)
West Brom (12) v Watford (6)
West Brom team news: Tony Pulis is likely to have an unchanged squad for the Premier League visit of Watford. Nacer Chadli (thigh) and Oliver Burke (hamstring) have resumed training but are lacking match sharpness.
Tony Pulis: “He (Marco Silva) has a better horse to ride this year than last year (when he was in charge at Hull). He’s been backed – they’ve spent quite a bit of money. They look a very capable team and it’ll be a tough game.”
Watford team news: Watford will have defender Miguel Britos available following a three-match supsension but midfielder Nathaniel Chalobah is out after it was confirmed he needs knee surgery. Sebastian Prodl (thigh), Younes Kaboul (hamstring), Craig Cathcart and Mauro Zarate (both knee) are not expected to feature.
Marco Silva: “We have started to build something important in our dressing room. The commitment I have felt and seen until now is really important.”
Last season: Watford 2 West Brom 0, West Brom 3 Watford 1
Last five league matches: West Brom W D L D L; Watford W D W L W
Top scorers: Jay Rodriguez (West Brom) 2; de Andrade Richarlison (Watford) 5
Match odds: H 5-4 A 12-5 D 21-10
Referee: Michael Oliver (Northumberland)
West Ham (18) v Swansea (15)
West Ham team news: Manuel Lanzini (knee) and Michail Antonio are available with Pedro Obiang (knock) the only absentee.
Slaven Bilic: “We beat Swansea twice last season. We’ll analyse them and all that, but to be fair we are at home and it is up to us.”
Swansea team news: Swansea skipper Leon Britton could return after recovering from a knee injury. On-loan Renato Sanches and Tammy Abraham could also return as Ki Sung-yueng (knee) and Nathan Dyer (Achilles) prepare to build their fitness in an under-23 game against Celtic.
Paul Clement: “The away form has been a help. We are defending better than we are attacking. We are working on that and I fully believe we will keep improving in that area. We have been able to find more space away from home and West Ham will want a win, which might give us room.”
Last season: West Ham 1 Swansea 0, Swansea 1 West Ham 4
Last five league matches: West Ham L L W D L; Swansea L W L D L
Top scorers: Javier Hernandez (West Ham) 3; Tammy Abraham & Jordan Ayew (Swansea) 3
Match odds: H 5-6 A 10-3 D 5-2
Referee: Roger East (Wiltshire)
Sunday October 1
Arsenal (7) v Brighton (13)
Arsenal team news: Arsenal could field Mesut Ozil, Alexis Sanchez and Alexandre Lacazette together for the first time. The Gunners are without Calum Chambers, Francis Coquelin and Santi Cazorla, while Danny Welbeck and Alex Iwobi are doubts.
Arsene Wenger: “Even if they only get 20 minutes, you have to convince people you have the qualities to do it and the courage to play and show your qualities.”
Brighton team news: Brighton will be without Tomer Hemed, who starts a three-match ban. Sam Baldock (calf) is still missing but Glenn Murray (ankle) has an outside chance of being involved. Steve Sidwell (back surgery) is recovering and Beram Kayal (broken leg) is sidelined.
Chris Hughton: “We know the player (Tomer Hemed), we still feel that there was no intent and that’s why we appealed, so we are very disappointed (with his three-match ban).”
Last season: No Corresponding fixture
Last five league matches: Arsenal L L W D W; Brighton L D W L W
Top scorers: Alexandre Lacazette (Arsenal) 4; Tomer Hemed & Pascal Gross (Brighton) 2
Match odds: H 2-9 A 12-1 D 5-1
Referee: Kevin Friend (Leicestershire)
Everton (14) v Burnley (9)
Everton team news: Everton will assess centre-backs Michael Keane (foot) and Phil Jagielka (hamstring). Oumar Niasse is set to return and Wayne Rooney (hand) has been passed fit to play. James McCarthy (knee) needs Under-23s game time before he makes his first-team comeback.
Ronald Koeman: “I am too long in this job to lose my confidence. Yes, I am worried about the situation and how we can turn it around, but I have enough confidence to be the same manager I was for the last six or seven years, when I was successful.”
Burnley team news: Jon Walters (knee) and Nahki Wells (ankle) will again sit out Burnley’s clash with Everton. The same is true of midfielder Dean Marney, who has been sidelined since January after rupturing knee ligaments.
Sean Dyche: “Ideally you want a competitive group of goalkeepers. (Nick) Pope’s got the shirt at the moment and done very well. He’s been sitting waiting for his chance and that’s come round. With Legs and Anders, you want that competitive element.”
Last season: Everton 3 Burnley 1, Burnley 2 Everton 1
Last five league matches: Everton D L L L W; Burnley L D W D D
Top scorers: Dominic Calvert-Lewin & Oumar Niasse (Everton) 3; Chris Wood (Burnley) 4
Match odds: H 8-13 A 5-1 D 13-5
Referee: Jonathan Moss (County Durham)
Newcastle (10) v Liverpool (5)
Newcastle team news: Newcastle striker Aleksandar Mitrovic is available after suspension and Florian Lejeune returns to contention after shaking off an ankle injury. Paul Dummett (hamstring) and Massadio Haidara (knee) missing.
Rafael Benitez: “I have talked in the past about the short blanket – if you cover your head, your feet are cold; if you cover your feet, your head is cold. Sometimes when you attack too much, you are exposed in defence and to find the balance is the key to have chances to win titles.”
Liverpool team news: Liverpool forward Sadio Mane is set to start after returning from a domestic suspension.
Midfielder Georginio Wijnaldum could face his former club at the expense of Emre Can. Midfielder Adam Lallana (thigh) and right-back Nathaniel Clyne (back) remain out.
Jurgen Klopp: “There are a few teams who are obviously flying. Does it mean the other teams should not try to fly also?”
Last season: No Corresponding fixture
Last five league matches: Newcastle L W W W L; Liverpool W W L D W
Top scorers: Aleksandar Mitrovic & Jamaal Lascelles (Newcastle) 2; Mohamed Salah (Liverpool) 6
Match odds: H 4-1 A 7-10 D 11-4
Referee: Craig Pawson (South Yorkshire)